Time course of cisplatin-induced nephrotoxicity and hepatotoxicity
نویسندگان
چکیده
منابع مشابه
Time course of cisplatin-induced nephrotoxicity and hepatotoxicity
BACKGROUND One of the main therapeutic limitations of cisplatin (CP) is nephrotoxicity which is time-dependent. OBJECTIVES The purpose of this study was to determine the optimal timing for initiation of CP toxicity. MATERIALS AND METHODS Sixty male and female Wistar rats were randomly divided into five groups. All the animals in groups 2-5 received single dose of CP (10 mg/kg; i.p.), and we...
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ژورنال
عنوان ژورنال: Journal of Nephropathology
سال: 2017
ISSN: 2251-8363,2251-8819
DOI: 10.15171/jnp.2017.28